SCHEMBL16693261

SCHEMBL16693261

C=C(C)C(=O)OCCc1ccc(/N=N/c2cc(C(=O)c3ccccc3)c(O)cc2O)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.39
HPGD P15428 3/20 0.37
LMNA P02545 3/20 0.37
MAPT P10636 3/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.37
RECQL P46063 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PPARA Q07869 7/20 0.36
PPARG P37231 7/20 0.36
PPARD Q03181 4/20 0.36
ELANE P08246 1/20 0.36
ALDH1A1 P00352 2/20 0.35
CYP1A2 P05177 1/20 0.35
PGR P06401 1/20 0.35
CYP2D6 P10635 1/20 0.35
SLC6A2 P23975 1/20 0.35
PDE4A P27815 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373648 1.00 L3MBTL1 (0.39) L3MBTL1HPGDLMNAMAPTKDM4E
SCHEMBL373404 0.94 PPARG (0.38) L3MBTL1HPGDLMNAMAPTKDM4E
SCHEMBL1803270 0.92 PPARA (0.34) L3MBTL1HPGDLMNAMAPTKDM4E
SCHEMBL3196968 0.92 PPARA (0.34) L3MBTL1HPGDLMNAMAPTKDM4E
SCHEMBL16693224 0.91 MAPT (0.47) L3MBTL1HPGDLMNAMAPTKDM4E
SCHEMBL7178326 0.90 HPGD (0.41) L3MBTL1HPGDLMNAMAPTKDM4E
SCHEMBL373543 0.90 HPGD (0.41) L3MBTL1HPGDLMNAMAPTKDM4E
SCHEMBL13269910 0.90 PPARA (0.34) L3MBTL1LMNAKDM4EPPARAPPARG
SCHEMBL13269909 0.90 PPARA (0.34) L3MBTL1LMNAKDM4EPPARAPPARG
SCHEMBL16693249 0.89 LMNA (0.38) L3MBTL1HPGDLMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064674-A1 METHOD FOR MANUFACTURING POLYMERIZABLE UV-ABSORBING DYE 興和株式会社 2015-05-07 WO disclosed