SCHEMBL16693281

SCHEMBL16693281

C=CC(=O)OCCc1ccc(/N=N/c2cc(C(=O)c3ccccc3)c(O)cc2OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
RECQL P46063 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ALOX5 P09917 5/20 0.44
TTR P02766 3/20 0.43
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 1/20 0.42
AKR1B10 O60218 1/20 0.41
AKR1B1 P15121 1/20 0.41
MET P08581 6/20 0.40
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA12 O43570 1/20 0.39
CA4 P22748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16693389 0.91 LMNA (0.38) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL16693252 0.91 MAPT (0.47) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL16693265 0.91 MAPT (0.48) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL16693386 0.90 L3MBTL1 (0.40) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL16693224 0.87 MAPT (0.47) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL16693300 0.86 MAPT (0.43) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL15359135 0.85 MAPT (0.46) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL16594788 0.85 MAPT (0.46) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL16693333 0.85 MAPT (0.54) MAPTLMNAKDM4ECYP3A4HPGD
SCHEMBL16693326 0.85 APP (0.42) MAPTLMNAKDM4ECYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064674-A1 METHOD FOR MANUFACTURING POLYMERIZABLE UV-ABSORBING DYE 興和株式会社 2015-05-07 WO disclosed