SCHEMBL16693252

SCHEMBL16693252

C=CC(=O)OCCOC(=O)c1ccc(/N=N/c2cc(C(=O)c3ccccc3)c(O)cc2OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.47
LMNA P02545 4/20 0.47
KDM4E B2RXH2 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP3A4 P08684 2/20 0.47
HPGD P15428 2/20 0.47
RECQL P46063 1/20 0.47
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.39
MEN1 O00255 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 3/20 0.38
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
CASP3 P42574 1/20 0.37
RAB9A P51151 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16693287 0.91 MAPT (0.38) MAPTLMNAKDM4EHSD17B10CYP3A4
SCHEMBL16693281 0.91 MAPT (0.47) MAPTLMNAKDM4EHSD17B10CYP3A4
SCHEMBL16693225 0.90 THRB (0.39) MAPTLMNAKDM4EHSD17B10CYP3A4
SCHEMBL16693300 0.88 MAPT (0.43) MAPTLMNAKDM4EHSD17B10CYP3A4
SCHEMBL16693230 0.87 MAPT (0.47) MAPTLMNAKDM4EHSD17B10CYP3A4
SCHEMBL16693265 0.87 MAPT (0.48) MAPTLMNAKDM4EHSD17B10CYP3A4
SCHEMBL16693250 0.85 THRB (0.41) MAPTLMNAHSD17B10HPGDRECQL
SCHEMBL16693389 0.82 LMNA (0.38) MAPTLMNAKDM4EHSD17B10CYP3A4
SCHEMBL16693386 0.80 L3MBTL1 (0.40) MAPTLMNAKDM4EHSD17B10CYP3A4
SCHEMBL16693324 0.79 RAB9A (0.38) MAPTLMNAKDM4EHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064674-A1 METHOD FOR MANUFACTURING POLYMERIZABLE UV-ABSORBING DYE 興和株式会社 2015-05-07 WO disclosed