Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16693248 | 0.91 | HPGD (0.42) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693302 | 0.91 | MAPT (0.49) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693268 | 0.89 | HPGD (0.36) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693329 | 0.89 | MAPT (0.40) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693234 | 0.87 | LMNA (0.38) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693249 | 0.84 | LMNA (0.38) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693320 | 0.84 | PTGES (0.40) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693258 | 0.84 | GAA (0.37) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693285 | 0.82 | MAPT (0.38) | LMNAHPGDMAPTKDM4ERECQL | |
| SCHEMBL16693264 | 0.82 | MAPT (0.51) | LMNAHPGDMAPTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015064674-A1 | METHOD FOR MANUFACTURING POLYMERIZABLE UV-ABSORBING DYE | 興和株式会社 | 2015-05-07 | — | — | WO | disclosed |
| US-8629263-B2 | Nucleoside phosphoramidates | GILEAD PHARMASSET LLC (US) | 2014-01-14 | — | — | US | disclosed |