SCHEMBL16693258

SCHEMBL16693258

C=C(C)C(=O)OCCNC(=O)c1cccc(/N=N/c2cc(C(=O)c3ccccc3)c(O)cc2OCC)c1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.37
PDE5A O76074 5/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 2/20 0.35
LMNA P02545 2/20 0.35
CYP3A4 P08684 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
RECQL P46063 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HCRTR1 O43613 1/20 0.34
RAB9A P51151 1/20 0.34
PTPN11 Q06124 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16693294 0.93 SIRT5 (0.37) TP53HPGDLMNACYP3A4KDM4E
SCHEMBL16693259 0.92 MAPT (0.43) GAAHPGDLMNACYP3A4KDM4E
SCHEMBL16693313 0.91 SMN1; SMN2 (0.38) HPGDLMNACYP3A4KDM4EMAPT
SCHEMBL16693234 0.88 LMNA (0.38) GAAHPGDLMNACYP3A4KDM4E
SCHEMBL16693311 0.85 NME4 (0.44) GAAHPGDLMNACYP3A4MAPT
SCHEMBL16693291 0.84 MAPT (0.43) GAAHPGDLMNACYP3A4KDM4E
SCHEMBL16693303 0.84 LMNA (0.40) GAAPDE5ATP53HPGDLMNA
SCHEMBL16693268 0.84 HPGD (0.36) PDE5AHPGDLMNACYP3A4KDM4E
SCHEMBL16693392 0.83 SIRT5 (0.41) HPGDLMNACYP3A4KDM4EMAPT
SCHEMBL16693285 0.82 MAPT (0.38) HPGDLMNACYP3A4KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064674-A1 METHOD FOR MANUFACTURING POLYMERIZABLE UV-ABSORBING DYE 興和株式会社 2015-05-07 WO disclosed