Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959566 | 0.72 | KMT2A (0.57) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL22634040 | 0.71 | MEN1 (0.49) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL27626467 | 0.70 | KMT2A (0.54) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL22372789 | 0.69 | TSHR (0.46) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL30507766 | 0.68 | CES1 (0.46) | LMNACYP2D6KMT2ACES1 | |
| SCHEMBL10361030 | 0.68 | CYP2D6 (0.51) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL953947 | 0.67 | KMT2A (0.50) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL4396455 | 0.67 | KMT2A (0.50) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL958241 | 0.67 | KMT2A (0.50) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL22645649 | 0.67 | LMNA (0.43) | HRH1MEN1LMNACYP2D6SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |