Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372789 | 0.79 | TSHR (0.46) | LMNAHRH1MEN1KMT2ACYP2D6 | |
| SCHEMBL22645614 | 0.78 | GBA1 (0.42) | LMNAHRH1MEN1KMT2ACYP2D6 | |
| SCHEMBL22372854 | 0.75 | ALDH1A1 (0.43) | LMNAHRH1MEN1KMT2ACYP2D6 | |
| SCHEMBL22372855 | 0.72 | SCN1A (0.45) | LMNAHRH1MEN1KMT2ACYP2D6 | |
| SCHEMBL22373044 | 0.71 | MEN1 (0.41) | LMNAHRH1MEN1KMT2ACYP2D6 | |
| SCHEMBL22374191 | 0.70 | CHRNB2 (0.42) | LMNAHRH1MEN1KMT2ACYP2D6 | |
| SCHEMBL1912949 | 0.70 | CHRNA7 (0.61) | HRH1MEN1KMT2ASCN1ASCN2A | |
| SCHEMBL2777615 | 0.70 | CHRM3 (0.58) | KMT2ACHRNA7SLC6A3MAPK1HIF1A | |
| SCHEMBL22373531 | 0.70 | ITGB3 (0.40) | LMNAHRH1MEN1KMT2ACYP2D6 | |
| SCHEMBL22372876 | 0.69 | MAPT (0.42) | LMNAHRH1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136330-B2 | Synthesis of labeled imidazo[1,2-A]pyrimidines | GENENTECH, INC. (US) | 2021-10-05 | — | — | US | disclosed |
| US-20200354369-A1 | SYNTHESIS OF LABELED IMIDAZO[1,2-A]PYRIMIDINES | GENENTECH, INC. (US) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136330-B2 | Synthesis of labeled imidazo[1,2-A]pyrimidines | TYMS, TYMP, PAICS | LMNA 2616/4885HRH1 4017/4885MEN1 531/4885 |
| US-20200354369-A1 | SYNTHESIS OF LABELED IMIDAZO[1,2-A]PYRIMIDINES | TYMS, TYMP, PAICS | LMNA 2616/4885HRH1 4017/4885MEN1 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.