Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.79 |
| ▸ | PDE4A | P27815 | 6/20 | 0.79 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.79 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.79 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.68 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.67 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.67 |
| ▸ | MC3R | P41968 | 1/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.67 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.67 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.67 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21381247 | 0.89 | PDE4A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4651994 | 0.88 | ADORA2A (0.88) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| Fluoride SCHEMBL30358487 | 0.87 | ADORA2A (0.85) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL516446 | 0.87 | ADORA2A (0.74) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL515570 | 0.85 | PDE4A (0.83) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5463424 | 0.85 | ADORA2A (0.72) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4145707 | 0.85 | ADORA2A (0.77) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16093733 | 0.84 | ADORA2A (0.70) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8861588 | 0.84 | PDE4A (0.75) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6291380 | 0.83 | ADORA2A (0.69) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651770-B1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF IN A SYNERGISTIC COMBINATION WITH CAFFEINE | ORTHO NUTRA LLC (US) | 2023-11-08 | — | — | EP | claimed |
| WO-2023064511-A9 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | Ingenious Ingredients, LP (US) | 2023-06-08 | — | — | WO | claimed |
| WO-2023064511-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | Ingenious Ingredients, LP (US) | 2023-04-20 | — | — | WO | claimed |
| US-20230115966-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | PX ING, LLC | 2023-04-13 | — | — | US | claimed |
| US-20230072854-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | PX ING, LLC | 2023-03-09 | — | — | US | claimed |
| US-11541020-B2 | Hexylamine salts and methods of using hexylamine | THERMOLIFE INTERNATIONAL, LLC (US) | 2023-01-03 | — | — | US | claimed |
| EP-4093296-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | Ingenious Ingredients, LP (US) | 2022-11-30 | — | — | EP | claimed |
| EP-3938341-A1 | HEXYLAMINE SALTS AND METHODS OF USING HEXYLAMINE | Thermolife International, LLC (US) | 2022-01-19 | — | — | EP | claimed |
| WO-2021151094-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | Ingenious Ingredients, LP (US) | 2021-07-29 | — | — | WO | claimed |
| US-20200405662-A1 | Hexylamine Salts and Methods of Using Hexylamine | THERMOLIFE INTERNATIONAL, LLC | 2020-12-31 | — | — | US | claimed |
| WO-2020214841-A1 | HEXYLAMINE SALTS AND METHODS OF USING HEXYLAMINE | THERMOLIFE INTERNATIONAL, LLC (US) | 2020-10-22 | — | — | WO | claimed |
| EP-3651770-A1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF IN A SYNERGISTIC COMBINATION WITH CAFFEINE | Ortho-Nutra LLC (US) | 2020-05-20 | — | — | EP | claimed |
| US-10398701-B2 | Theacrine-based supplement and method of use thereof in a synergistic combination with caffeine | ORTHO-NUTRA, LLC (US) | 2019-09-03 | — | — | US | claimed |
| WO-2018211425-A1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF IN A SYNERGISTIC COMBINATION WITH CAFFEINE | ORTHO-NUTRA, LLC (US) | 2018-11-22 | — | — | WO | claimed |
| US-20180104248-A1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF IN A SYNERGISTIC COMBINATION WITH CAFFEINE | ORTHO-NUTRA, LLC (US) | 2018-04-19 | — | — | US | claimed |
| CN-105992521-A | TeraPinine-based supplements and methods of use thereof | 奥索努特拉有限责任公司 | 2016-10-05 | — | — | CN | claimed |
| EP-3068240-A1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF | Ortho-Nutra LLC (US) | 2016-09-21 | — | — | EP | claimed |
| WO-2015073576-A1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF | ORTHO-NUTRA, LLC (US) | 2015-05-21 | — | — | WO | claimed |
| US-20150132280-A1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF | ORTHO-NUTRA, LLC (US) | 2015-05-14 | — | — | US | claimed |
| CN-100402093-C | Medicine used in medical breath diagnosis | YONGJIAN MA (CN) | 2008-07-16 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405662-A1 | Hexylamine Salts and Methods of Using Hexylamine | SLC6A2, CPT1B, GYS1 | ADORA2A 824/4885PDE4A 1859/4885PDE4B 1657/4885 |
| US-11541020-B2 | Hexylamine salts and methods of using hexylamine | SLC6A2, CPT1B, GYS1 | ADORA2A 824/4885PDE4A 1859/4885PDE4B 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.