Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.70 |
| ▸ | PDE4A | P27815 | 4/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.70 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.63 |
| ▸ | MC3R | P41968 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.63 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.63 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16697212 | 0.84 | ADORA2A (0.79) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4145707 | 0.83 | ADORA2A (0.77) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21381247 | 0.83 | PDE4A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL316760 | 0.82 | ADORA2B (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8861588 | 0.81 | PDE4A (0.75) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23974594 | 0.80 | ADORA2A (0.68) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL515931 | 0.80 | ADORA2A (0.68) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5411063 | 0.80 | ADORA2A (0.68) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1200300 | 0.80 | ADORA2A (0.68) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11675524 | 0.79 | PDE4A (0.71) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160030476-A1 | Compositions, Methods And Devices For Promoting Wound Healing And Reducing Infection | IASIS MOLECULAR SCIENCES (US) | 2016-02-04 | — | — | US | disclosed |
| EP-2967076-A2 | COMPOSITIONS, METHODS AND DEVICES FOR PROMOTING WOUND HEALING AND REDUCING INFECTION | Iasis Molecular Sciences (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153238-A9 | COMPOSITIONS, METHODS AND DEVICES FOR PROMOTING WOUND HEALING AND REDUCING INFECTION | IASIS MOLECULAR SCIENCES (US) | 2014-12-04 | — | — | WO | disclosed |
| WO-2014153238-A2 | COMPOSITIONS, METHODS AND DEVICES FOR PROMOTING WOUND HEALING AND REDUCING INFECTION | IASIS MOLECULAR SCIENCES (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160030476-A1 | Compositions, Methods And Devices For Promoting Wound Healing And Reducing Infection | MMP8, IL1B, MMP1 | ADORA2A 2760/4885PDE4A 2212/4885PDE4B 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.