Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.74 |
| ▸ | PDE4A | P27815 | 4/20 | 0.74 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.74 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.67 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.67 |
| ▸ | MC3R | P41968 | 1/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.67 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.67 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.67 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisdionin B SCHEMBL29896692 | 0.90 | ADORA2B (0.74) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL315740 | 0.89 | ADORA2B (0.82) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10018599 | 0.88 | ADORA2B (0.72) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4651994 | 0.88 | ADORA2A (0.88) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| Bisdionin D SCHEMBL16120988 | 0.87 | ADORA2B (0.79) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| Fluoride SCHEMBL30358487 | 0.87 | ADORA2A (0.85) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16697212 | 0.87 | ADORA2A (0.79) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| Bisdionin C SCHEMBL10018600 | 0.87 | CHIT1 (0.75) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL516018 | 0.86 | PDE4A (0.78) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7384278 | 0.85 | ADORA2B (0.68) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651770-B1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF IN A SYNERGISTIC COMBINATION WITH CAFFEINE | ORTHO NUTRA LLC (US) | 2023-11-08 | — | — | EP | claimed |
| WO-2023064511-A9 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | Ingenious Ingredients, LP (US) | 2023-06-08 | — | — | WO | claimed |
| WO-2023064511-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | Ingenious Ingredients, LP (US) | 2023-04-20 | — | — | WO | claimed |
| US-20230115966-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | PX ING, LLC | 2023-04-13 | — | — | US | claimed |
| CN-115811955-A | Bioactive compositions based on para-xanthines and methods of use thereof | 独创成分有限合伙公司 | 2023-03-17 | — | — | CN | claimed |
| US-20230072854-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | PX ING, LLC | 2023-03-09 | — | — | US | claimed |
| US-11541020-B2 | Hexylamine salts and methods of using hexylamine | THERMOLIFE INTERNATIONAL, LLC (US) | 2023-01-03 | — | — | US | claimed |
| EP-4093296-A1 | PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | Ingenious Ingredients, LP (US) | 2022-11-30 | — | — | EP | claimed |
| CN-115279197-A | Enhanced caffeine-containing beverage composition | 奥索努特拉有限责任公司 | 2022-11-01 | — | — | CN | claimed |
| EP-3938341-A1 | HEXYLAMINE SALTS AND METHODS OF USING HEXYLAMINE | Thermolife International, LLC (US) | 2022-01-19 | — | — | EP | claimed |
| US-20150132280-A1 | THEACRINE-BASED SUPPLEMENT AND METHOD OF USE THEREOF | ORTHO-NUTRA, LLC (US) | 2015-05-14 | — | — | US | claimed |
| CN-100402093-C | Medicine used in medical breath diagnosis | YONGJIAN MA (CN) | 2008-07-16 | — | — | CN | claimed |
| EP-0167566-A4 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | SUNSHINE ABRAHAM (US) | 1987-06-29 | — | — | EP | claimed |
| EP-0165308-A4 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | RICHARDSON VICKS INC (US) | 1986-05-16 | — | — | EP | claimed |
| US-4567183-A | SYNERGISTIC, POTENTIATION | ANALGESIC ASSOCIATES (US) | 1986-01-28 | — | — | US | claimed |
| EP-0167566-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | SUNSHINE, Abraham (US) | 1986-01-15 | — | — | EP | claimed |
| EP-0165308-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | RICHARDSON VICKS INC (US) | 1985-12-27 | — | — | EP | claimed |
| US-4558051-A | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same | RICHARDSON-VICKS, INC. (US) | 1985-12-10 | — | — | US | claimed |
| WO-1985002542-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | SUNSHINE ABRAHAM | 1985-06-20 | — | — | WO | claimed |
| WO-1985002540-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | RICHARDSON-VICKS, INC. (US) | 1985-06-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541020-B2 | Hexylamine salts and methods of using hexylamine | SLC6A2, CPT1B, GYS1 | ADORA2A 824/4885PDE4A 1859/4885PDE4B 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.