SCHEMBL16698002

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14152247	0.85	CNR2 (0.60)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL25256887	0.84	PPP1CA (0.47)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL28214040	0.80	RPA1 (0.50)	KDM4ETDP1DHODHCNR1RPA1
	SCHEMBL2837730	0.79	KDM4E (0.54)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL15439882	0.79	PIK3CA (0.48)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL16705800	0.78	ALDH1A1 (0.50)	KDM4ENR4A2CNR1CNR2LMNA
	SCHEMBL16714148	0.78	CYP1A2 (0.59)	KDM4EDHODHLMNAALDH1A1HPGD
	SCHEMBL21494746	0.78	KDM4E (0.52)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL319073	0.78	KDM4E (0.52)	KDM4EALOX15TSHRACMSDTDP1
	SCHEMBL316936	0.76	PIK3CA (0.46)	KDM4EALOX15TSHRACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.