Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | LIG1 | P18858 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21433657 | 0.72 | KDM1A (0.46) | KDM1ARCOR1MAOBHTR2CHTR2B | |
| SCHEMBL2103232 | 0.71 | — | — | |
| SCHEMBL1779485 | 0.71 | — | — | |
| SCHEMBL14313656 | 0.71 | KDM1A (0.36) | KDM1ARCOR1KCNH2MAOBKDM1B | |
| SCHEMBL12295868 | 0.69 | KDM1A (0.68) | KDM1ARCOR1KCNH2MAOBKDM1B | |
| SCHEMBL265495 | 0.69 | KDM1A (0.48) | KDM1ARCOR1KCNH2MAOBKDM1B | |
| SCHEMBL14804315 | 0.69 | KDM1A (0.48) | KDM1ARCOR1KCNH2MAOBKDM1B | |
| SCHEMBL4800650 | 0.69 | TSHR (0.42) | KDM1ARCOR1KCNH2MAOBKDM1B | |
| SCHEMBL883113 | 0.69 | KDM1A (0.68) | KDM1ARCOR1KCNH2MAOBKDM1B | |
| SCHEMBL6519587 | 0.69 | TSHR (0.42) | KDM1ARCOR1KCNH2MAOBKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027692-C | Process for producing dienamide derivative | ROUSSEL UCLAF CO (FR) | 1995-02-22 | — | — | CN | claimed |
| EP-2907802-B1 | CYCLOPROPANAMINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |
| CN-109153636-A | Cyclopropyl-amide compound as dual LSD1/HDAC inhibitor | 朱比连特比利斯有限公司 | 2019-01-04 | — | — | CN | disclosed |
| US-9751885-B2 | Cyclopropanamine compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-09-05 | — | — | US | disclosed |
| US-20150266881-A1 | CYCLOPROPANAMINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-09-24 | — | — | US | disclosed |
| CN-102952056-A | Heptafluoroisopropylphenyl group contained diphenyl pyrroline compound and its use | SINOCHEM CORP | 2013-03-06 | — | — | CN | disclosed |
| EP-2486002-A1 | SUBSTITUTED HETEROARYL- AND ARYL- CYCLOPROPYLAMINE ACETAMIDES AND THEIR USE | Oryzon Genomics, S.A. (ES) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042217-A1 | SUBSTITUTED HETEROARYL- AND ARYL- CYCLOPROPYLAMINE ACETAMIDES AND THEIR USE | ORYZON GENOMICS S.A. (ES) | 2011-04-14 | — | — | WO | disclosed |
| CN-101952267-A | Cyclopropylamine Derivatives | ABBOTT LAB | 2011-01-19 | — | — | CN | disclosed |
| CN-1684960-B | Delta1 pyrrolines used as pesticides | BAYER CROPSCIENCE AG | 2010-05-26 | — | — | CN | disclosed |
| CN-101472887-A | Cyclopropylamine derivatives as modulators of the histamine H3 receptor | ABBOTT LAB (US) | 2009-07-01 | — | — | CN | disclosed |
| CN-1684960-A | Delta1 pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2005-10-19 | — | — | CN | disclosed |
| CN-1491211-A | Delta for controlling pests1-pyrrolines | �ݶ�ũ�����ѧ�ɷݹ�˾ | 2004-04-21 | — | — | CN | disclosed |
| CN-1466571-A | Preparation of delta1Process for preparing pyrrolines | �ݶ�ũ�����ѧ�ɷݹ�˾ | 2004-01-07 | — | — | CN | disclosed |
| CN-1045576-A | Pesticide | WELLCOME FOUND (GB) | 1990-09-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266881-A1 | CYCLOPROPANAMINE COMPOUND AND USE THEREOF | BHMT, HNMT, KDM1A | KDM1A 3/4885RCOR1 111/4885KCNH2 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.