Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL16699833

CCC[n+]1ccccc1.O=C([O-])C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
CHRM1 P11229 2/20 0.42
ACHE P22303 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
ABCB11 O95342 1/20 0.42
ESR1 P03372 1/20 0.42
PGR P06401 1/20 0.42
HTR1A P08908 1/20 0.42
DRD1 P21728 1/20 0.42
TBXA2R P21731 1/20 0.42
PTGS1 P23219 1/20 0.42
PDE4A P27815 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3103642 0.89 ACHE (0.53) CHRM2ADRA2AADORA3CHRM1ACHE
Trifluoroacetic Acid SCHEMBL16700146 0.88 ACHE (0.61) CHRM2ADRA2AADORA3CHRM1ACHE
Cetylpyridinium SCHEMBL3217090 0.86 ACHE (0.65) CHRM2ADRA2AADORA3CHRM1ACHE
Trifluoroacetic Acid SCHEMBL6115378 0.85 KMT2A (0.41) CHRM2ADRA2AADORA3CHRM1ACHE
Acetic Acid SCHEMBL28627961 0.84 ACHE (0.48) CHRM2ADRA2AADORA3CHRM1ACHE
Trifluoroacetic Acid SCHEMBL16700556 0.82 HTT (0.46) ACHEKMT2AHSP90AA1HTTMEN1
Trifluoroacetic Acid SCHEMBL16700661 0.79 PABPC1 (0.44) KMT2ARAD52SMN1; SMN2HSP90AA1LMNA
Trifluoroacetic Acid SCHEMBL27849527 0.78 ACHE (0.57) CHRM2ADRA2AADORA3CHRM1ACHE
Trifluoromethanesulfonic Acid SCHEMBL6852192 0.78 KCNH2 (0.42) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL97814 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244987-B1 SEPARATIONS WITH IONIC LIQUID SOLVENTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2022-06-22 EP claimed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP claimed
US-20150133711-A1 Separations With Ionic Liquid Solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP 2015-05-14 US claimed
EP-3244987-B1 SEPARATIONS WITH IONIC LIQUID SOLVENTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2022-06-22 EP disclosed
US-10227274-B2 Separations with ionic liquid solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-03-12 US disclosed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP disclosed
US-20150133711-A1 Separations With Ionic Liquid Solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP 2015-05-14 US disclosed