Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3103642

CCCC[n+]1ccccc1.O=C([O-])C(F)(F)F

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.53
CHRM2 P08172 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
CHRM1 P11229 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
ABCB11 O95342 1/20 0.53
ESR1 P03372 1/20 0.53
PGR P06401 1/20 0.53
HTR1A P08908 1/20 0.53
DRD1 P21728 1/20 0.53
TBXA2R P21731 1/20 0.53
PTGS1 P23219 1/20 0.53
PDE4A P27815 1/20 0.53
ADRA1A P35348 1/20 0.53
OPRM1 P35372 1/20 0.53
DRD3 P35462 1/20 0.53
KCNH2 Q12809 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL16700146 0.95 ACHE (0.61) ACHECHRM2ADRA2AADORA3CHRM1
Cetylpyridinium SCHEMBL3217090 0.93 ACHE (0.65) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoroacetic Acid SCHEMBL16699833 0.89 CHRM2 (0.42) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoroacetic Acid SCHEMBL27849527 0.89 ACHE (0.57) ACHECHRM2ADRA2AADORA3CHRM1
Bicarbonate SCHEMBL28058344 0.87 ACHE (0.63) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoroacetamide SCHEMBL27957724 0.86 ACHE (0.53) ACHECHRM2ADRA2AADORA3CHRM1
Acetic Acid SCHEMBL4538473 0.85 ACHE (0.61) ACHECHRM2ADRA2AADORA3CHRM1
Propionic Acid SCHEMBL1006275 0.84 ACHE (0.59) ACHECHRM2ADRA2AADORA3CHRM1
Bicarbonate SCHEMBL28058346 0.83 ACHE (0.68) ACHECHRM2ADRA2AADORA3CHRM1
Trifluoroacetic Acid SCHEMBL6115378 0.82 KMT2A (0.41) ACHECHRM2ADRA2AADORA3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244987-B1 SEPARATIONS WITH IONIC LIQUID SOLVENTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2022-06-22 EP claimed
CN-107427758-A Utilize the separation of ion liquid solvent 切弗朗菲利浦化学公司 2017-12-01 CN claimed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP claimed
US-20150133711-A1 Separations With Ionic Liquid Solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP 2015-05-14 US claimed
CN-120136654-A Method for preparing bicyclopropyl high-energy fuel by catalyzing olefin with ionic liquid 河南大学 2025-06-13 CN disclosed
EP-3244987-B1 SEPARATIONS WITH IONIC LIQUID SOLVENTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2022-06-22 EP disclosed
US-10227274-B2 Separations with ionic liquid solvents CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-03-12 US disclosed
CN-107427758-A Utilize the separation of ion liquid solvent 切弗朗菲利浦化学公司 2017-12-01 CN disclosed
EP-3244987-A1 SEPARATIONS WITH IONIC LIQUID SOLVENTS Chevron Phillips Chemical Company LP (US) 2017-11-22 EP disclosed
EP-2872489-B1 SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2016-12-21 EP disclosed
US-9512080-B2 Synthesis of acridinium compounds by N-alkylation of acridans SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2016-12-06 US disclosed
CN-103556481-B A kind of preparation method of polyacrylonitrile doughnut encapsulating material DONGHUA UNIVERSITY (CN) 2016-05-04 CN disclosed
CN-103556282-A Preparation method for novel warm-keeping type polyacrylonitrile hollow fiber UNIV DONGHUA 2014-02-05 CN disclosed
CN-103556481-A Method for preparing polyacrylonitrile hollow fiber packaging material UNIV DONGHUA 2014-02-05 CN disclosed
CN-103521098-A Method for preparing polyacrylonitrile hollow fiber membrane UNIV DONGHUA 2014-01-22 CN disclosed
WO-2014011762-A1 SYNTHESIS OF ACRIDINIUM COMPOUNDS BY N-ALKYLATION OF ACRIDANS SIEMENS HEAL THCARE DIAGNOSTICS INC. (US) 2014-01-16 WO disclosed
CN-103515118-A Electrolyte for double-electric-layer capacitor ZHOU MINGJIE 2014-01-15 CN disclosed
EP-2215063-B1 FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS SIEMENS HEALTHCARE DIAGNOSTICS (US) 2013-10-30 EP disclosed
US-8293908-B2 Facile N-alkylation of acridine compounds in ionic liquids SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2012-10-23 US disclosed
US-20100256380-A1 FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256380-A1 FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS ACR, MGMT, DNMT3A ACHE 875/4885CHRM2 764/4885ADRA2A 2222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.