Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 2/20 | 0.43 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL16700757 | 0.87 | ALPG (0.42) | ALPGPLAAALPLCYP2D6TSHR | |
| SCHEMBL464450 | 0.85 | — | — | |
| Nitric Acid SCHEMBL16700778 | 0.84 | AGTR1 (0.44) | CYP2D6TSHRCYP2C19HIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL20262982 | 0.83 | ALPG (0.46) | ALPGPLAAALPLCYP2D6TSHR | |
| SCHEMBL28104483 | 0.83 | ALPG (0.44) | ALPGPLAAALPLCYP2D6TSHR | |
| Bromide SCHEMBL28236460 | 0.83 | ALPG (0.44) | ALPGPLAAALPLCYP2D6TSHR | |
| Acetic Acid SCHEMBL28296570 | 0.82 | ALPG (0.49) | ALPGPLAAALPLCYP2D6TSHR | |
| SCHEMBL27862505 | 0.81 | ALPG (0.44) | ALPGPLAAALPLCYP2D6TSHR | |
| Nitric Acid SCHEMBL16701122 | 0.81 | FDPS (0.45) | ALPGPLAATSHRALDH1A1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL1681989 | 0.80 | ALPG (0.42) | ALPGPLAAALPLCYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3244987-B1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2022-06-22 | — | — | EP | claimed |
| CN-107427758-A | Utilize the separation of ion liquid solvent | 切弗朗菲利浦化学公司 | 2017-12-01 | — | — | CN | claimed |
| EP-3244987-A1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | Chevron Phillips Chemical Company LP (US) | 2017-11-22 | — | — | EP | claimed |
| US-20150133711-A1 | Separations With Ionic Liquid Solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2015-05-14 | — | — | US | claimed |
| EP-3244987-B1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2022-06-22 | — | — | EP | disclosed |
| US-10227274-B2 | Separations with ionic liquid solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2019-03-12 | — | — | US | disclosed |
| CN-107427758-A | Utilize the separation of ion liquid solvent | 切弗朗菲利浦化学公司 | 2017-12-01 | — | — | CN | disclosed |
| EP-3244987-A1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | Chevron Phillips Chemical Company LP (US) | 2017-11-22 | — | — | EP | disclosed |
| US-20150133711-A1 | Separations With Ionic Liquid Solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2015-05-14 | — | — | US | disclosed |