Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | USP14 | P54578 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 5/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670089 | 1.00 | ESR1 (0.34) | ESR1ESR2USP14BRD4ADORA3 | |
| SCHEMBL1077417 | 0.85 | ESR1 (0.38) | ESR1ESR2BRD4 | |
| SCHEMBL1077420 | 0.85 | ESR1 (0.38) | ESR1ESR2BRD4 | |
| SCHEMBL1667700 | 0.84 | BRD4 (0.36) | ESR1ESR2USP14BRD4ADORA3 | |
| SCHEMBL1667699 | 0.84 | BRD4 (0.36) | ESR1ESR2USP14BRD4ADORA3 | |
| SCHEMBL1670092 | 0.82 | ESR1 (0.34) | ESR1ESR2USP14BRD4 | |
| SCHEMBL2311182 | 0.82 | BRD4 (0.34) | ESR1ESR2USP14BRD4 | |
| SCHEMBL2313824 | 0.82 | BRD4 (0.34) | ESR1ESR2USP14BRD4 | |
| SCHEMBL1667683 | 0.80 | BRD4 (0.34) | ESR1ESR2USP14BRD4 | |
| SCHEMBL1667686 | 0.80 | BRD4 (0.34) | ESR1ESR2USP14BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |