SCHEMBL16701341

SCHEMBL16701341

[N-]=[N+]=NS(=O)(=O)c1ccc(OC(=O)OCC2COC(=O)O2)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.33
MMP9 P14780 3/20 0.33
MMP14 P50281 3/20 0.33
MMP8 P22894 1/20 0.33
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18099388 0.82 BDKRB1 (0.36) MMP2MMP9MMP14MMP8ALDH1A1
SCHEMBL230593 0.77 L3MBTL1 (0.41)
SCHEMBL9644015 0.71 L3MBTL1 (0.38) ALDH1A1LMNA
SCHEMBL16711675 0.69 L3MBTL1 (0.33)
SCHEMBL18092295 0.67 CA1 (0.30)
SCHEMBL21781851 0.66 L3MBTL1 (0.41) ALDH1A1
SCHEMBL1952351 0.66 SMN1; SMN2 (0.36) ALDH1A1
SCHEMBL29329710 0.66 SMN1; SMN2 (0.36) ALDH1A1
SCHEMBL1301565 0.66 L3MBTL1 (0.37) ALDH1A1
SCHEMBL22693775 0.65 THRB (0.42) ALDH1A1LMNAGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9562114-B2 Cyclic carbonate azide AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2017-02-07 US disclosed
US-20160280805-A1 Cyclic Carbonate Azide WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2016-09-29 US disclosed
EP-3066088-A1 CYCLIC CARBONATE AZIDE Akzo Nobel Chemicals International B.V. (NL) 2016-09-14 EP disclosed
WO-2015067532-A1 CYCLIC CARBONATE AZIDE AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160280805-A1 Cyclic Carbonate Azide ATXN2L, ATXN10, CYCS MMP2 4215/4885MMP9 3133/4885MMP14 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.