Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29899133 | 1.00 | TDP1 (0.43) | TDP1JUNNFKB1NFKB2RELA | |
| SCHEMBL29919207 | 0.89 | TDP1 (0.41) | TDP1JUNNFKB1NFKB2RELA | |
| SCHEMBL16701782 | 0.89 | TDP1 (0.41) | TDP1JUNNFKB1NFKB2RELA | |
| SCHEMBL249075 | 0.84 | TDP1 (0.44) | TDP1ALDH1A1PKM | |
| SCHEMBL29417448 | 0.84 | TDP1 (0.44) | TDP1ALDH1A1PKM | |
| SCHEMBL1204974 | 0.84 | TDP1 (0.44) | TDP1JUNNFKB1NFKB2RELA | |
| SCHEMBL29708780 | 0.84 | TDP1 (0.44) | TDP1JUNNFKB1NFKB2RELA | |
| SCHEMBL16454314 | 0.80 | HSP90AA1 (0.31) | — | |
| SCHEMBL21749477 | 0.80 | TDP1 (0.41) | TDP1JUNNFKB1NFKB2RELA | |
| SCHEMBL3075824 | 0.80 | TDP1 (0.41) | TDP1JUNNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083860-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | FUKANG SHANGHAI HEALTH TECH CO LTD (CN) | 2024-03-14 | — | — | US | disclosed |
| EP-4303217-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Fukang (Shanghai) Health Technology Co., Ltd. (CN) | 2024-01-10 | — | — | EP | disclosed |
| US-20230089582-A1 | 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | KPC PHARMACEUTICALS INC (CN) | 2023-03-23 | — | — | US | disclosed |
| EP-4083024-A1 | 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | KPC Pharmaceuticals, Inc. (CN) | 2022-11-02 | — | — | EP | disclosed |
| CN-115028621-A | Aromatic compound, preparation method and application thereof | 甫康（上海）健康科技有限责任公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113454069-A | 1, 2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| WO-2021104288-A1 | 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 昆药集团股份有限公司 | 2021-06-03 | — | — | WO | disclosed |
| EP-3068777-B1 | 1-(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-27 | — | — | EP | disclosed |
| EP-3068777-B1 | 1-(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-27 | — | — | EP | disclosed |
| US-9723840-B2 | 1-(pyridazin-3-yl)-imidazolidin-2-one derivatives as herbicides | SYNGENTA LIMITED (GB) | 2017-08-08 | — | — | US | disclosed |
| US-9723840-B2 | 1-(pyridazin-3-yl)-imidazolidin-2-one derivatives as herbicides | SYNGENTA LIMITED (GB) | 2017-08-08 | — | — | US | disclosed |
| US-9723840-B2 | 1-(pyridazin-3-yl)-imidazolidin-2-one derivatives as herbicides | SYNGENTA LIMITED (GB) | 2017-08-08 | — | — | US | disclosed |
| EP-3068777-A1 | 1 -(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | Syngenta Participations AG (CH) | 2016-09-21 | — | — | EP | disclosed |
| US-20160262395-A1 | 1-(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20160262395-A1 | 1-(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20160262395-A1 | 1-(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| WO-2015067701-A1 | 1 -(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015067701-A1 | 1 -(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160262395-A1 | 1-(PYRIDAZIN-3-YL)-IMIDAZOLIDIN-2-ONE DERIVATIVES AS HERBICIDES | DDT, CBR3, CBR1 | TDP1 1882/4885JUN 4465/4885NFKB1 3672/4885 |
| US-20230089582-A1 | 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | THRB, THRA, TSHR | TDP1 1882/4885JUN 1268/4885NFKB1 3281/4885 |
| US-20240083860-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SLC10A1, GOT1, CYP46A1 | TDP1 3435/4885JUN 807/4885NFKB1 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.