Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545097 | 0.86 | TSHR (0.45) | MAPTALDH1A1LMNASMN1; SMN2GLA | |
| SCHEMBL7242144 | 0.80 | MAPT (0.49) | MAPT | |
| SCHEMBL2475462 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL2595067 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL7698910 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL10961012 | 0.71 | MAPT (0.49) | MEN1KMT2APARP10NQO1MAPT | |
| SCHEMBL11698604 | 0.70 | NQO1 (0.47) | MEN1KMT2APARP10NQO1MAPT | |
| SCHEMBL1904633 | 0.70 | POLQ (0.50) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17769749 | 0.70 | TSHR (0.43) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8006543 | 0.69 | PARP10 (0.58) | MEN1KMT2APARP10NQO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066098-A1 | SUBSTITUTED URACILS AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067630-A1 | SUBSTITUTED URACILS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-05-14 | — | — | WO | disclosed |