SCHEMBL1670430

SCHEMBL1670430

O=C1CN(c2ccccc2)C(=O)C1C1=NC=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.38
▸ NPC1 O15118 3/20 0.38
▸ RAB9A P51151 3/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ MAPT P10636 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ POLB P06746 2/20 0.35
▸ SIGMAR1 Q99720 3/20 0.34
▸ GRM2 Q14416 1/20 0.34
▸ CTSG P08311 2/20 0.33
▸ USP2 O75604 2/20 0.33
▸ FADS1 O60427 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ FPR1 P21462 1/20 0.33
▸ CMA1 P23946 1/20 0.33
▸ GFER P55789 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9370584 0.78 KMT2A (0.44) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL1670432 0.75 KMT2A (0.38) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL10580265 0.69 MEN1 (0.45) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL5138888 0.68 LMNA (0.42) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL18328089 0.67 KMT2A (0.42) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL15240944 0.65 MEN1 (0.58) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL17070928 0.65 GRM2 (0.49) KMT2ANPC1RAB9AMEN1GAA
SCHEMBL1027868 0.65 KMT2A (0.40) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL11606165 0.64 MEN1 (0.47) KMT2ANPC1RAB9AMEN1MAPT
SCHEMBL7190353 0.64 HTT (0.49) KMT2ANPC1RAB9AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2488578-B1 STABILISER COMBINATIONS FOR HALOGENATED POLYMERS IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO KG (DE) 2014-04-30 — — EP disclosed
EP-2545116-A1 STABILIZER MIXTURES FOR HALOGEN-CONTAINING PLASTICS BY UNDERWATER PELLETIZATION IKA Innovative Kunststoffaufbereitung GmbH&Co. KG (DE) 2013-01-16 — — EP disclosed
EP-2488578-A1 STABILISER COMBINATIONS FOR HALOGENATED POLYMERS IKA Innovative Kunststoffaufbereitung GmbH&Co. KG (DE) 2012-08-22 — — EP disclosed
WO-2011110395-A1 STABILIZER MIXTURES FOR HALOGEN-CONTAINING PLASTICS BY UNDERWATER PELLETIZATION IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) 2011-09-15 — — WO disclosed
WO-2011045168-A1 STABILISER COMBINATIONS FOR HALOGENATED POLYMERS IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) 2011-04-21 — — WO disclosed
EP-2113007-A1 STABILISER COMBINATIONS FOR HALOGENATED POLYMERS IKA Innovative Kunststoffaufbereitung Gmbh & Co.Kg (DE) 2009-11-04 — — EP disclosed
WO-2008071534-A1 STABILISER COMBINATIONS FOR HALOGENATED POLYMERS IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO.KG (DE) 2008-06-19 — — WO disclosed
EP-1771507-A2 STABILISER SYSTEM FOR HALOGENATED POLYMERS Artemis Research GmbH & Co.KG (DE) 2007-04-11 — — EP disclosed
WO-2006013040-A2 STABILISER SYSTEM FOR HALOGENATED POLYMERS ARTEMIS RESEARCH GMBH & CO. KG (DE) 2006-02-09 — — WO disclosed
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