SCHEMBL18328089

SCHEMBL18328089

O=CC1C(=O)CN(c2ccccc2)C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ NPC1 O15118 3/20 0.42
▸ RAB9A P51151 3/20 0.42
▸ MAPT P10636 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ POLB P06746 2/20 0.39
▸ USP2 O75604 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ CTSG P08311 2/20 0.36
▸ DDB1 Q16531 1/20 0.36
▸ CRBN Q96SW2 1/20 0.36
▸ CMA1 P23946 1/20 0.36
▸ ATM Q13315 1/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10580265 0.74 MEN1 (0.45) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL9370584 0.73 KMT2A (0.44) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL5193549 0.71 LMNA (0.47) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL5138888 0.69 LMNA (0.42) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL17070928 0.69 GRM2 (0.49) KMT2AMEN1NPC1RAB9AGAA
SCHEMBL1027868 0.69 KMT2A (0.40) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL7190353 0.68 HTT (0.49) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL4102659 0.68 POLB (0.46) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL15362058 0.68 MEN1 (0.47) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL1670430 0.67 KMT2A (0.38) KMT2AMEN1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10254456-B2 Polarizing plate composition, polarizing plate protective film, polarizer, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-04-09 — — US disclosed
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 — — US disclosed
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 — — US disclosed
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