Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279680 | 0.79 | MEN1 (0.41) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL1670432 | 0.78 | KMT2A (0.38) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL1670430 | 0.78 | KMT2A (0.38) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL10580265 | 0.76 | MEN1 (0.45) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL5138888 | 0.74 | LMNA (0.42) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL18328089 | 0.73 | KMT2A (0.42) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL1027868 | 0.70 | KMT2A (0.40) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL17070928 | 0.70 | GRM2 (0.49) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL3498051 | 0.70 | ALDH1A1 (0.50) | KMT2ARAB9AMEN1ALDH1A1GFER | |
| SCHEMBL225262 | 0.69 | KMT2A (0.47) | KMT2ANPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103804108-B | A kind of method preparing primary amine | 沈阳药科大学 | 2016-08-03 | — | — | CN | disclosed |
| EP-0409163-B1 | Novel cyclic vinylogous N-hydroxy-N-methylureas useful as 5-lipoxygenase inhibitors | MERRELL DOW PHARMA (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5109010-A | Lipoxygenase inhibitor; antiasthmic, antiarthritic agent | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5026861-A | Antiarthritic asthma agent, lipoxygenase inhibitors | MERRELL DOW PHARMACEUTICALS (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0409163-A2 | Novel cyclic vinylogous N-hydroxy-N-methylureas useful as 5-lipoxygenase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-01-23 | — | — | EP | disclosed |