Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.55 |
| ▸ | TK1 | P04183 | 6/20 | 0.47 |
| ▸ | TK2 | O00142 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704357 | 0.91 | RNASE1 (0.56) | RNASE1TK1TK2 | |
| SCHEMBL25752670 | 0.88 | RNASE1 (0.59) | RNASE1TK1TK2 | |
| SCHEMBL1334035 | 0.87 | RNASE1 (0.71) | RNASE1TK1TK2 | |
| SCHEMBL7922859 | 0.87 | RNASE1 (0.58) | RNASE1TK1TK2 | |
| SCHEMBL7922857 | 0.87 | RNASE1 (0.58) | RNASE1TK1TK2 | |
| SCHEMBL1334032 | 0.87 | RNASE1 (0.71) | RNASE1TK1TK2 | |
| SCHEMBL16704351 | 0.87 | RNASE1 (0.71) | RNASE1TK1TK2 | |
| SCHEMBL3912314 | 0.85 | RNASE1 (0.54) | RNASE1TK1TK2 | |
| SCHEMBL3912309 | 0.85 | RNASE1 (0.54) | RNASE1TK1TK2 | |
| SCHEMBL4578740 | 0.85 | TOP2A (0.58) | RNASE1TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029346-B1 | Irreversible inhibitors of DNA polymerase beta | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-05-12 | — | — | US | disclosed |