SCHEMBL25752670

SCHEMBL25752670

CC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1ON1C(=O)c2ccccc2C1=O

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.59
TK1 P04183 7/20 0.49
TK2 O00142 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16704351 0.91 RNASE1 (0.71) RNASE1TK1TK2
SCHEMBL7922859 0.91 RNASE1 (0.58) RNASE1TK1TK2
SCHEMBL7922857 0.91 RNASE1 (0.58) RNASE1TK1TK2
SCHEMBL1334035 0.91 RNASE1 (0.71) RNASE1TK1TK2
SCHEMBL1334032 0.91 RNASE1 (0.71) RNASE1TK1TK2
SCHEMBL16704350 0.88 RNASE1 (0.55) RNASE1TK1TK2
SCHEMBL4578740 0.85 TOP2A (0.58) RNASE1TK1TK2
SCHEMBL3912314 0.85 RNASE1 (0.54) RNASE1TK1TK2
SCHEMBL3912309 0.85 RNASE1 (0.54) RNASE1TK1TK2
SCHEMBL29760775 0.85 TOP2A (0.58) RNASE1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES Nuclera Nucleics Ltd. (GB) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES RNGTT, POLM, POLRMT RNASE1 26/4885TK1 259/4885TK2 437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.