Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 6/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672805 | 0.84 | BRD4 (0.38) | BRD4HSP90AB1ERN1CREBBPAR | |
| SCHEMBL1672807 | 0.84 | BRD4 (0.38) | BRD4HSP90AB1ERN1CREBBPAR | |
| SCHEMBL1672787 | 0.83 | ERN1 (0.38) | BRD4NSD3ESR1ERN1BTK | |
| SCHEMBL1682605 | 0.83 | HSP90AB1 (0.35) | BRD4HSP90AB1NSD3ESR1ERN1 | |
| SCHEMBL11899095 | 0.83 | HSP90AB1 (0.35) | BRD4HSP90AB1NSD3ESR1ERN1 | |
| SCHEMBL1672789 | 0.83 | ERN1 (0.38) | BRD4NSD3ESR1ERN1BTK | |
| SCHEMBL1670490 | 0.82 | BRD4 (0.35) | BRD4HSP90AB1NSD3ESR1ERN1 | |
| SCHEMBL1672863 | 0.78 | BRD4 (0.38) | BRD4ERN1BTKCREBBPAR | |
| SCHEMBL1672861 | 0.78 | BRD4 (0.38) | BRD4ERN1BTKCREBBPAR | |
| SCHEMBL16193791 | 0.76 | GPBAR1 (0.35) | BRD4HSP90AB1ESR1ERN1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |