Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826874 | 0.86 | GAA (0.55) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL10317272 | 0.86 | ALDH1A1 (0.50) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL1505552 | 0.84 | ALDH1A1 (0.66) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL595444 | 0.84 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL9861415 | 0.83 | L3MBTL1 (0.49) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL595150 | 0.83 | ALDH1A1 (0.69) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL16705221 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL18039308 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL31599394 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TARBP2GAAMAPT | |
| SCHEMBL31661270 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TARBP2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209446-A | GPR120 agonists for the treatment of type ii diabetes | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |
| US-5068343-A | Fungicides for plants | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |