SCHEMBL16705226

SCHEMBL16705226

Cc1ccc(C2(c3ccc(C)cc3)C=Cc3c4c(c5ccccc5c3O2)-c2ccccc2C4(C)C)cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25604294 0.93
SCHEMBL25844384 0.93 PGR (0.32) PGRHSD17B10
SCHEMBL3154868 0.92 HSD17B10 (0.32) HSD17B10
SCHEMBL25716068 0.90 ALDH1A1 (0.32)
SCHEMBL25604646 0.90
SCHEMBL25604649 0.90
SCHEMBL3151355 0.90 PGR (0.32) PGR
SCHEMBL25604295 0.89 GPR84 (0.31)
SCHEMBL25604645 0.89
SCHEMBL10102320 0.89 NPSR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651914-B1 PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS TRANSITIONS OPTICAL INC (US) 2015-05-13 EP disclosed