Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670526 | 1.00 | BRD4 (0.36) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1672986 | 0.86 | ERN1 (0.40) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1672985 | 0.86 | ERN1 (0.40) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1670734 | 0.85 | MLYCD (0.38) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1670732 | 0.85 | MLYCD (0.38) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1672902 | 0.81 | BRD4 (0.35) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1672903 | 0.81 | BRD4 (0.35) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1670529 | 0.81 | BRD4 (0.38) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1672805 | 0.79 | BRD4 (0.38) | BRD4MLYCDERN1BRD2CREBBP | |
| SCHEMBL1672807 | 0.79 | BRD4 (0.38) | BRD4MLYCDERN1BRD2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |