SCHEMBL1672986 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	ERN1	O75460	2/20	0.40

▸	KDM1A	O60341	2/20	0.35

▸	BRD4	O60885	12/20	0.34

▸	BRD2	P25440	5/20	0.34

▸	BRD3	Q15059	3/20	0.34

▸	CREBBP	Q92793	3/20	0.34

▸	MLYCD	O95822	1/20	0.33

▸	ESR1	P03372	2/20	0.32

▸	ESR2	Q92731	2/20	0.32

▸	MGLL	Q99685	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1672985	1.00	ERN1 (0.40)	ERN1KDM1ABRD4BRD2BRD3
SCHEMBL1670528	0.86	BRD4 (0.36)	ERN1BRD4BRD2CREBBPMLYCD
SCHEMBL1670526	0.86	BRD4 (0.36)	ERN1BRD4BRD2CREBBPMLYCD
SCHEMBL1672988	0.83	ERN1 (0.40)	ERN1BRD4BRD2BRD3CREBBP
SCHEMBL11898800	0.80	ERN1 (0.38)	ERN1KDM1ABRD4BRD2BRD3
SCHEMBL1672787	0.80	ERN1 (0.38)	ERN1KDM1ABRD4BRD2BRD3
SCHEMBL1672789	0.80	ERN1 (0.38)	ERN1KDM1ABRD4BRD2BRD3
SCHEMBL1682416	0.80	ERN1 (0.38)	ERN1KDM1ABRD4BRD2BRD3
SCHEMBL1672896	0.76	ERN1 (0.38)	ERN1BRD4BRD2CREBBPMLYCD
SCHEMBL1672894	0.76	ERN1 (0.38)	ERN1BRD4BRD2CREBBPMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011042477-A1	SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS	KARO BIO AB (SE)	2011-04-14	—	—	WO	claimed