Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733944 | 0.82 | CYP11B2 (0.32) | CYP11B2 | |
| SCHEMBL9607538 | 0.77 | CYP11B2 (0.42) | CYP11B2KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24483790 | 0.76 | CYP11B2 (0.45) | CYP11B2KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12121231 | 0.76 | CYP11B2 (0.45) | CYP11B2KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21719113 | 0.75 | TRPA1 (0.32) | MEN1KMT2ATRPA1 | |
| SCHEMBL21863433 | 0.74 | CYP11B2 (0.44) | CYP11B2KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21503625 | 0.74 | CYP11B2 (0.44) | CYP11B2KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15608616 | 0.74 | CYP11B2 (0.44) | CYP11B2KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24977549 | 0.74 | MPO (0.38) | CYP11B2CYP1A2MPO | |
| Hydrochloric Acid SCHEMBL18283885 | 0.72 | CYP11B2 (0.42) | CYP11B2KDM4ECYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |
| EP-2549875-B1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK SHARP & DOHME (US) | 2015-05-13 | — | — | EP | disclosed |