SCHEMBL16705662

SCHEMBL16705662

OCCCCCCCCOc1ccc(O)cc1

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.68
LTA4H P09960 3/20 0.58
ALDH2 P05091 3/20 0.50
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50
DRD3 P35462 1/20 0.50
APP P05067 1/20 0.47
PRMT1 Q99873 2/20 0.47
F2 P00734 1/20 0.47
PLAU P00749 1/20 0.47
ST14 Q9Y5Y6 1/20 0.47
GAA P10253 1/20 0.47
PRMT5 O14744 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10920258 1.00 NR5A1 (0.68) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL8178321 1.00 NR5A1 (0.68) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL25797567 1.00 NR5A1 (0.68) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL2465060 1.00 NR5A1 (0.68) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL2974464 0.98 NR5A1 (0.64) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL14191191 0.94 NR5A1 (0.61) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL5414694 0.94 NR5A1 (0.61) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL25798514 0.94 NR5A1 (0.61) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL8183422 0.94 NR5A1 (0.61) NR5A1LTA4HALDH2DRD2DRD4
SCHEMBL4448744 0.91 LTA4H (0.61) NR5A1LTA4HDRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119435-A1 COMPOSITIONS OF MECHANICALLY INTERLOCKED, TOPOLOGICALLY COMPLEX CROSSLINKERS AND POLYMERS AND METHODS OF MAKING AND USING SAME WASHINGTON UNIVERSITY (US) 2022-04-21 US disclosed
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2021-08-17 US disclosed
US-10830935-B2 Phase difference plate, circularly polarizing plate, and image display device ZEON CORPORATION (JP) 2020-11-10 US disclosed
US-20200048213-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2020-02-13 US disclosed
EP-3564221-A1 POLYMERIZABLE COMPOUND, MIXTURE, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC BODY, POLARIZING SHEET, DISPLAY DEVICE, AND ANTIREFLECTIVE FILM Zeon Corporation (JP) 2019-11-06 EP disclosed
US-20190315893-A1 POLYMERIZABLE COMPOUND, MIXTURE, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC PRODUCT, POLARIZING PLATE, DISPLAY DEVICE, AND ANTIREFLECTION FILM ZEON CORPORATION (JP) 2019-10-17 US disclosed
EP-2910986-B1 RETARDER, CIRCULARLY POLARISING PLATE, AND IMAGE DISPLAY DEVICE ZEON CORP (JP) 2019-03-13 EP disclosed
US-10173992-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2019-01-08 US disclosed
EP-2871192-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORP (JP) 2018-06-20 EP disclosed
US-9995865-B2 Phase difference plate, circularly polarizing plate, and image display device ZEON CORPORATION (JP) 2018-06-12 US disclosed
US-9586917-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2017-03-07 US disclosed
US-9586917-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2017-03-07 US disclosed
US-20160280672-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2016-09-29 US disclosed
US-20160280672-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2016-09-29 US disclosed
US-20150277010-A1 PHASE DIFFERENCE PLATE, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE ZEON CORPORATION (JP) 2015-10-01 US disclosed
US-20150277010-A1 PHASE DIFFERENCE PLATE, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE ZEON CORPORATION (JP) 2015-10-01 US disclosed
EP-2910986-A1 RETARDER, CIRCULARLY POLARISING PLATE, AND IMAGE DISPLAY DEVICE Zeon Corporation (JP) 2015-08-26 EP disclosed
US-20150175564-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2015-06-25 US disclosed
US-20150175564-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2015-06-25 US disclosed
EP-2871192-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND Zeon Corporation (JP) 2015-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10173992-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound PYM1, C5, C1S NR5A1 3807/4885LTA4H 852/4885ALDH2 3381/4885
US-20200048213-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND PDE8A, MAPT, PLK4 NR5A1 3350/4885LTA4H 2097/4885ALDH2 4311/4885
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound PDE8A, MAPT, PLK4 NR5A1 3350/4885LTA4H 2097/4885ALDH2 4311/4885
US-20160280672-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND PYM1, C5, C1S NR5A1 3807/4885LTA4H 852/4885ALDH2 3381/4885
US-20220119435-A1 COMPOSITIONS OF MECHANICALLY INTERLOCKED, TOPOLOGICALLY COMPLEX CROSSLINKERS AND POLYMERS AND METHODS OF MAKING AND USING SAME PCNA, SMC4, ERCC5 NR5A1 4820/4885LTA4H 3004/4885ALDH2 3373/4885
US-20190315893-A1 POLYMERIZABLE COMPOUND, MIXTURE, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC PRODUCT, POLARIZING PLATE, DISPLAY DEVICE, AND ANTIREFLECTION FILM CCNA1, CCNA2, ADRA1A NR5A1 1182/4885LTA4H 830/4885ALDH2 4006/4885
US-20150175564-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND PYM1, C5, C1S NR5A1 3807/4885LTA4H 852/4885ALDH2 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.