SCHEMBL1670634

SCHEMBL1670634

Cc1cnn(C)c1-c1c(-c2ccc(O)cc2)c(Cl)n(C)c1C(=N)NO

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1672287 0.80 ESR1 (0.32)
SCHEMBL1670636 0.80 USP7 (0.30)
SCHEMBL1671210 0.79 USP7 (0.30)
SCHEMBL1672900 0.76 IDO1 (0.36)
SCHEMBL1670619 0.76
SCHEMBL1670828 0.73 GAA (0.30) GAA
SCHEMBL1671012 0.73
SCHEMBL1670318 0.72 SENP1 (0.30)
SCHEMBL1670522 0.72 SENP1 (0.30)
SCHEMBL1670567 0.71 GAA (0.30) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011042477-A1 SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS KARO BIO AB (SE) 2011-04-14 WO disclosed