Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671210 | 0.86 | USP7 (0.30) | — | |
| SCHEMBL1670619 | 0.83 | — | — | |
| SCHEMBL1670634 | 0.80 | AKT1 (0.31) | — | |
| SCHEMBL1671012 | 0.80 | — | — | |
| SCHEMBL1670522 | 0.79 | SENP1 (0.30) | SENP1 | |
| SCHEMBL1670318 | 0.79 | SENP1 (0.30) | SENP1 | |
| SCHEMBL1672285 | 0.79 | ESR1 (0.32) | ESR1ESR2SENP1 | |
| SCHEMBL1672283 | 0.79 | ESR1 (0.32) | ESR1ESR2SENP1 | |
| SCHEMBL1672900 | 0.76 | IDO1 (0.36) | — | |
| SCHEMBL1670633 | 0.75 | GSK3B (0.34) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |