Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1945586 | 0.76 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1670666 | 0.73 | KMT2A (0.67) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL966981 | 0.73 | EPHX1 (0.73) | SMN1; SMN2ALDH1A1EPHX1EPHX2RAB9A | |
| SCHEMBL27440890 | 0.73 | EPHX1 (0.73) | SMN1; SMN2ALDH1A1EPHX1EPHX2RAB9A | |
| SCHEMBL12812331 | 0.73 | EPHX1 (0.73) | SMN1; SMN2ALDH1A1EPHX1EPHX2RAB9A | |
| SCHEMBL8394304 | 0.73 | EPHX1 (0.73) | SMN1; SMN2ALDH1A1EPHX1EPHX2RAB9A | |
| SCHEMBL19940662 | 0.73 | EPHX1 (0.73) | SMN1; SMN2ALDH1A1EPHX1EPHX2RAB9A | |
| SCHEMBL31517118 | 0.73 | HNF4A (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL1479704 | 0.73 | HNF4A (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| Cyclohexane SCHEMBL8419079 | 0.72 | HNF4A (0.60) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385948-A1 | FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | Torrent Pharmaceuticals Limited (IN) | 2011-11-16 | — | — | EP | disclosed |
| WO-2011045811-A1 | FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-21 | — | — | WO | disclosed |