Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1945585 | 0.78 | RAB9A (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16607158 | 0.78 | KMT2A (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10131753 | 0.76 | CCR2 (0.56) | KMT2AMEN1ALDH1A1EPHX2RAB9A | |
| SCHEMBL1670902 | 0.75 | CHRNB2 (0.73) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL10337975 | 0.74 | CHRNB2 (0.58) | KMT2AALDH1A1LMNANPSR1GAA | |
| SCHEMBL1670668 | 0.73 | MEN1 (0.61) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1672799 | 0.73 | TSHR (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL516891 | 0.72 | ALDH1A1 (0.82) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1649572 | 0.72 | CHRNB2 (0.68) | KMT2AALDH1A1LMNANPSR1GAA | |
| SCHEMBL11007801 | 0.71 | CHRNB2 (0.72) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385948-A1 | FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | Torrent Pharmaceuticals Limited (IN) | 2011-11-16 | — | — | EP | disclosed |
| WO-2011045811-A1 | FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-21 | — | — | WO | disclosed |