Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646653 | 0.82 | PTGS2 (0.52) | PTGS2PTGS1P2RY6 | |
| SCHEMBL6093316 | 0.82 | PTGS2 (0.65) | PTGS2PTGS1P2RY6 | |
| SCHEMBL4751105 | 0.82 | PTGS2 (0.65) | PTGS2PTGS1P2RY6 | |
| SCHEMBL27916566 | 0.82 | PTGS2 (0.65) | PTGS2PTGS1P2RY6 | |
| Fluoride SCHEMBL28028189 | 0.81 | PTGS2 (0.63) | PTGS2PTGS1P2RY6 | |
| SCHEMBL27648680 | 0.81 | PTGS2 (0.63) | PTGS2PTGS1P2RY6 | |
| SCHEMBL16914776 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1P2RY6 | |
| SCHEMBL5667657 | 0.79 | P2RY6 (0.55) | PTGS2PTGS1P2RY6 | |
| Benzene SCHEMBL6629703 | 0.79 | PTGS2 (0.62) | PTGS2PTGS1 | |
| Trifluoroacetic Acid SCHEMBL27628779 | 0.78 | PTGS2 (0.60) | PTGS2PTGS1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770432-B2 | Deuterated benzopyran compounds and the use in the treatment of pain and inflammation | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2017-09-26 | — | — | US | disclosed |
| US-9770432-B2 | Deuterated benzopyran compounds and the use in the treatment of pain and inflammation | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2017-09-26 | — | — | US | disclosed |
| US-9763914-B2 | Deuterated benzopyran compounds and application thereof | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2017-09-19 | — | — | US | disclosed |
| US-20170020843-A1 | DEUTERATED BENZOPYRAN COMPOUNDS AND APPLICATION THEREOF | INFLAMAX PHARMACEUTICALS LIMITED (CN) | 2017-01-26 | — | — | US | disclosed |
| US-20170020843-A1 | DEUTERATED BENZOPYRAN COMPOUNDS AND APPLICATION THEREOF | INFLAMAX PHARMACEUTICALS LIMITED (CN) | 2017-01-26 | — | — | US | disclosed |
| US-20160287556-A1 | DEUTERATED BENZOPYRAN COMPOUNDS AND APPLICATION THEREOF | INFLAMAX PHARMACEUTICALS LIMITED (CN) | 2016-10-06 | — | — | US | disclosed |
| US-9371305-B2 | Deuterated benzopyran compounds and application thereof | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-21 | — | — | US | disclosed |
| US-20150133538-A1 | Deuterated Benzopyran Compounds and Application Thereof | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133538-A1 | Deuterated Benzopyran Compounds and Application Thereof | PTGS2, HPGDS, PTGS1 | PTGS2 1/4885PTGS1 3/4885P2RY6 505/4885 |
| US-20160287556-A1 | DEUTERATED BENZOPYRAN COMPOUNDS AND APPLICATION THEREOF | PTGS2, HPGDS, PTGS1 | PTGS2 1/4885PTGS1 3/4885P2RY6 505/4885 |
| US-20170020843-A1 | DEUTERATED BENZOPYRAN COMPOUNDS AND APPLICATION THEREOF | PTGS2, HPGDS, PTGS1 | PTGS2 1/4885PTGS1 3/4885P2RY6 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.