SCHEMBL16707487

SCHEMBL16707487

Cc1cc(SC(F)(F)F)c(C)c(C)c1SC(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16707473 0.83 SMN1; SMN2 (0.33) HTR2ASMN1; SMN2HTR2CHTR2B
SCHEMBL16707491 0.83 HTR2A (0.33) HTR2ASMN1; SMN2
SCHEMBL16707522 0.77 SMN1; SMN2 (0.36) HTR2ASMN1; SMN2HTR2CHTR2B
SCHEMBL16707486 0.74 HTR2A (0.32) HTR2A
SCHEMBL16707488 0.73 HTR2A (0.35) HTR2ASMN1; SMN2
SCHEMBL16707513 0.73 HTR2A (0.39) HTR2ASMN1; SMN2
SCHEMBL16707478 0.73 SMN1; SMN2 (0.34) HTR2ASMN1; SMN2HTR2CHTR2B
SCHEMBL16707485 0.72 RAPGEF4 (0.32) HTR2ASMN1; SMN2HTR2CHTR2B
SCHEMBL16707489 0.72 ALDH1A1 (0.37) HTR2ASMN1; SMN2HTR2CHTR2B
SCHEMBL16707490 0.71 HTR2A (0.31) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647218-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-05-09 US disclosed
US-20150129849-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-05-14 US disclosed