SCHEMBL16707490

SCHEMBL16707490

Cc1c(C)c(C)c(SC(F)(F)F)c(C)c1C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16707486 0.97 HTR2A (0.32) HTR2A
SCHEMBL13725004 0.75 KDM4E (0.36) HTR2A
SCHEMBL9215593 0.73
SCHEMBL16707487 0.71 HTR2A (0.32) HTR2A
SCHEMBL7477600 0.66 HTR2A (0.31) HTR2A
SCHEMBL16707484 0.66 SMN1; SMN2 (0.41) HTR2A
SCHEMBL16707489 0.65 ALDH1A1 (0.37) HTR2A
SCHEMBL16707473 0.64 SMN1; SMN2 (0.33) HTR2A
SCHEMBL21614301 0.64 SMN1; SMN2 (0.33) HTR2A
SCHEMBL13724955 0.62 KDM4E (0.40) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647218-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-05-09 US disclosed
US-20150129849-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-05-14 US disclosed