SCHEMBL1670799

SCHEMBL1670799

Cc1oc(Cl)c(C)c1-c1c(-c2ccc(O)cc2)c(Br)n(C)c1C(N)=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.31
GRIA4 P48058 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1672889 0.87 SENP1 (0.30) SENP1
SCHEMBL1672887 0.87 SENP1 (0.30) SENP1
SCHEMBL1672892 0.83 SENP1 (0.31) SENP1
SCHEMBL1672956 0.73 SENP1 (0.30) SENP1
SCHEMBL1672957 0.73 SENP1 (0.30) SENP1
SCHEMBL1670036 0.70 PREP (0.31)
SCHEMBL1672959 0.70 SENP1 (0.31) SENP1
SCHEMBL12801021 0.69 SENP1 (0.34) SENP1
SCHEMBL1652989 0.68 PTPN1 (0.37) SENP1
SCHEMBL1670563 0.67 GRIA4 (0.39) SENP1GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011042477-A1 SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS KARO BIO AB (SE) 2011-04-14 WO claimed