Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 10/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670503 | 0.76 | AR (0.39) | GRIA4ARSENP1KDM4EALDH1A1 | |
| SCHEMBL1670817 | 0.75 | MLYCD (0.40) | AR | |
| SCHEMBL1670860 | 0.69 | AR (0.46) | GRIA4ARGRIA2FNTAFNTB | |
| SCHEMBL12988421 | 0.68 | ALOX5 (0.41) | ALDH1A1 | |
| SCHEMBL14675674 | 0.67 | XDH (0.37) | PTGER4 | |
| SCHEMBL1670799 | 0.67 | SENP1 (0.31) | GRIA4SENP1 | |
| SCHEMBL12801021 | 0.65 | SENP1 (0.34) | SENP1 | |
| SCHEMBL13195240 | 0.65 | ALOX5 (0.47) | KDM4EMAPK14 | |
| SCHEMBL1672959 | 0.61 | SENP1 (0.31) | SENP1 | |
| SCHEMBL1672956 | 0.61 | SENP1 (0.30) | SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |