SCHEMBL16708

SCHEMBL16708

O=S(=O)(Cl)c1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502516 0.80 ABCC9 (0.44)
SCHEMBL329369 0.78
SCHEMBL329370 0.76
SCHEMBL30817869 0.76
SCHEMBL7826145 0.76
SCHEMBL41731 0.76
SCHEMBL1260157 0.76
SCHEMBL28235881 0.74 ACP1 (0.42)
SCHEMBL27656783 0.74 ACP1 (0.42)
SCHEMBL27656791 0.74 SLC40A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081574-A Flame-retardant PET (polyethylene terephthalate) adhesive tape and preparation method thereof 常州市白鹭电器有限公司 2024-12-06 CN claimed
EP-1265858-B1 HYDROGEN REDUCTION OF SULFONYL CHLORIDES TO THIOLS DU PONT (US) 2004-05-19 EP claimed
US-6667421-B2 Hydrogenating an aryl sulfonyl chloride with hydrogen in a solvent in the presence of a palladium catalyst and a base whose conjugate acid pka is &gt;/=2 E. I. DU PONT DE NEMOURS AND COMPANY 2003-12-23 US claimed
US-20030055290-A1 Hydrogen reduction of sulfonyl chlorides to thiols THE TEXAS A&M UNIVERSITY SYSTEM 2003-03-20 US claimed
EP-1265858-A1 HYDROGEN REDUCTION OF SULFONYL CHLORIDES TO THIOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-12-18 EP claimed
WO-2001066517-A1 HYDROGEN REDUCTION OF SULFONYL CHLORIDES TO THIOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-13 WO claimed
EP-4573088-A1 HETEROCYCLE RBM39 MODULATORS Recursion Pharmaceuticals, Inc. (US) 2025-06-25 EP disclosed
CN-119409685-B 4- (1- (Azaacyl-3-butyl) -1H-imidazol-2-yl) anilides PKM2 agonists 南京医科大学 2025-04-25 CN disclosed
CN-119409685-A 4- (1- (Azaacyl-3-butyl) -1H-imidazol-2-yl) anilides PKM2 agonists 南京医科大学 2025-02-11 CN disclosed
CN-119081574-A Flame-retardant PET (polyethylene terephthalate) adhesive tape and preparation method thereof 常州市白鹭电器有限公司 2024-12-06 CN disclosed
US-20240092770-A1 Heterocycle RMB39 Modulators RECURSION PHARMACEUTICALS, INC. 2024-03-21 US disclosed
WO-2024039689-A1 HETEROCYCLE RBM39 MODULATORS RECURSION PHARMACEUTICALS, INC. (US) 2024-02-22 WO disclosed
CN-114957053-B Oxoethylene compound or pharmaceutically acceptable salt thereof, preparation method and application thereof, pharmaceutical composition and application thereof 中国医学科学院医药生物技术研究所 2023-12-22 CN disclosed
US-4230868-A α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles ELI LILLY AND COMPANY (US) 1980-10-28 US disclosed
US-4196125-A VIRICIDES ELI LILLY AND COMPANY (US) 1980-04-01 US disclosed
US-4174454-A VIRICIDES ELI LILLY AND COMPANY (US) 1979-11-13 US disclosed
US-4128586-A Catalytic reduction of aromatic sulfonyl halides with hydrogen sulfide to yield aromatic thiols ALLIED CHEMICAL CORPORATION (US) 1978-12-05 US disclosed
US-4118742-A VIRICIDES ELI LILLY AND COMPANY (US) 1978-10-03 US disclosed
US-4118573-A ANTIVIRAL AGENTS ELI LILLY AND COMPANY (US) 1978-10-03 US disclosed
US-4018790-A VIRICIDES ELI LILLY AND COMPANY (US) 1977-04-19 US disclosed