SCHEMBL502516

SCHEMBL502516

O=S(=O)(c1nccs1)c1nccs1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 1/20 0.44
ABCC8 Q09428 1/20 0.44
KCNJ11 Q14654 1/20 0.44
KCNJ8 Q15842 1/20 0.44
NAMPT P43490 3/20 0.43
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 2/20 0.42
TSHR P16473 1/20 0.42
NOS1 P29475 1/20 0.42
SLC40A1 Q9NP59 1/20 0.41
FBP1 P09467 1/20 0.39
PDK1 Q15118 1/20 0.39
ACP1 P24666 2/20 0.37
NLRP3 Q96P20 1/20 0.36
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP2C9 P11712 1/20 0.35
EDNRA P25101 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28965986 0.86 SLC40A1 (0.44) ABCC9ABCC8KCNJ11KCNJ8NAMPT
SCHEMBL329369 0.82
SCHEMBL9097096 0.81 POLB (0.50) ABCC9ABCC8KCNJ11KCNJ8NAMPT
SCHEMBL41731 0.80
SCHEMBL7826145 0.80
SCHEMBL16708 0.80
SCHEMBL329370 0.80
SCHEMBL1260157 0.80
SCHEMBL30817869 0.80
SCHEMBL4732573 0.78 ABCC9 (0.45) ABCC9ABCC8KCNJ11KCNJ8NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2990431-B1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS BOEING CO (US) 2024-03-27 EP claimed
EP-4332169-A2 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS The Boeing Company (US) 2024-03-06 EP claimed
CN-113559264-A Methods of treating microbial infections including mastitis 罗达制药公司 2021-10-29 CN claimed
CN-113144197-A Method of treating topical microbial infections 罗达制药公司 2021-07-23 CN claimed
CN-110845436-A Thiazolesulfone compound and preparation and application thereof 合肥锦绣田园化工科技有限公司 2020-02-28 CN claimed
CN-110204716-A Polyimide oligomers and resin system 波音公司 2019-09-06 CN claimed
CN-105384932-B Nano-modified backbone of polyimides with difunctional and mixed-functional endcaps 波音公司 2019-06-04 CN claimed
US-9670325-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2017-06-06 US claimed
US-9505864-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2016-11-29 US claimed
US-20160208053-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS THE BOEING COMPANY 2016-07-21 US claimed
CN-102307933-A Oligomers with diphenylethynyl endcaps BOEING CO 2012-01-04 CN claimed
US-8063168-B2 Oligomers with di-phenylethynyl endcaps THE BOEING COMPANY (US) 2011-11-22 US claimed
WO-2010141106-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS THE BOEING COMPANY (US) 2010-12-09 WO claimed
US-20100204412-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS THE BOEING COMPANY 2010-08-12 US claimed
US-20100204485-A1 POLYACETYLINIC OLIGOMERS THE BOEING COMPANY 2010-08-12 US claimed
CN-1433396-A Pharmaceutical compounds NICOX SA (FR) 2003-07-30 CN claimed
US-6569954-B1 Interpenetrating polymer networks THE BOEING COMPANY 2003-05-27 US claimed
CN-1358178-A Pharmaceutical compounds NICOX SA (FR) 2002-07-10 CN claimed
CN-1354740-A Pharmaceutical compounds NICOX SA (FR) 2002-06-19 CN claimed
US-5645925-A POLYMER BLEND BOEING COMPANY (US) 1997-07-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204485-A1 POLYACETYLINIC OLIGOMERS AADAC, ACMSD, ECPAS ABCC9 1793/4885ABCC8 2522/4885KCNJ11 3021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.