SCHEMBL502516

SCHEMBL502516

O=S(=O)(c1nccs1)c1nccs1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCC9 O60706 1/20 0.44
▸ ABCC8 Q09428 1/20 0.44
▸ KCNJ11 Q14654 1/20 0.44
▸ KCNJ8 Q15842 1/20 0.44
▸ NAMPT P43490 3/20 0.43
▸ ALDH1A1 P00352 4/20 0.42
▸ HSD17B10 Q99714 2/20 0.42
▸ TSHR P16473 1/20 0.42
▸ NOS1 P29475 1/20 0.42
▸ SLC40A1 Q9NP59 1/20 0.41
▸ FBP1 P09467 1/20 0.39
▸ PDK1 Q15118 1/20 0.39
▸ ACP1 P24666 2/20 0.37
▸ NLRP3 Q96P20 1/20 0.36
▸ LMNA P02545 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ EDNRA P25101 1/20 0.35
▸ SLC6A4 P31645 1/20 0.35
▸ ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28965986 0.86 SLC40A1 (0.44) ABCC9ABCC8KCNJ11KCNJ8NAMPT
SCHEMBL329369 0.82 — —
SCHEMBL9097096 0.81 POLB (0.50) ABCC9ABCC8KCNJ11KCNJ8NAMPT
SCHEMBL30817869 0.80 — —
SCHEMBL41731 0.80 — —
SCHEMBL16708 0.80 — —
SCHEMBL7826145 0.80 — —
SCHEMBL329370 0.80 — —
SCHEMBL1260157 0.80 — —
SCHEMBL11046642 0.78 GAA (0.52) ABCC9ABCC8KCNJ11KCNJ8NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2990431-B1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS BOEING CO (US) 2024-03-27 — — EP claimed
EP-4332169-A2 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS The Boeing Company (US) 2024-03-06 — — EP claimed
CN-113559264-A Methods of treating microbial infections including mastitis 罗达制药公司 2021-10-29 — — CN claimed
CN-113144197-A Method of treating topical microbial infections 罗达制药公司 2021-07-23 — — CN claimed
CN-110845436-A Thiazolesulfone compound and preparation and application thereof 合肥锦绣田园化工科技有限公司 2020-02-28 — — CN claimed
CN-110204716-A Polyimide oligomers and resin system 波音公司 2019-09-06 — — CN claimed
CN-105384932-B Nano-modified backbone of polyimides with difunctional and mixed-functional endcaps 波音公司 2019-06-04 — — CN claimed
US-9670325-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2017-06-06 — — US claimed
US-9505864-B2 Nanomodified backbones for polyimides with difunctional and mixed-functionality endcaps THE BOEING COMPANY (US) 2016-11-29 — — US claimed
US-20160208053-A1 NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS THE BOEING COMPANY 2016-07-21 — — US claimed
CN-102307933-A Oligomers with diphenylethynyl endcaps BOEING CO 2012-01-04 — — CN claimed
US-8063168-B2 Oligomers with di-phenylethynyl endcaps THE BOEING COMPANY (US) 2011-11-22 — — US claimed
WO-2010141106-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS THE BOEING COMPANY (US) 2010-12-09 — — WO claimed
US-20100204412-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS THE BOEING COMPANY 2010-08-12 — — US claimed
US-20100204485-A1 POLYACETYLINIC OLIGOMERS THE BOEING COMPANY 2010-08-12 — — US claimed
CN-1433396-A Pharmaceutical compounds NICOX SA (FR) 2003-07-30 — — CN claimed
US-6569954-B1 Interpenetrating polymer networks THE BOEING COMPANY 2003-05-27 — — US claimed
CN-1358178-A Pharmaceutical compounds NICOX SA (FR) 2002-07-10 — — CN claimed
CN-1354740-A Pharmaceutical compounds NICOX SA (FR) 2002-06-19 — — CN claimed
US-5645925-A POLYMER BLEND BOEING COMPANY (US) 1997-07-08 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204485-A1 POLYACETYLINIC OLIGOMERS AADAC, ACMSD, ECPAS ABCC9 1793/4885ABCC8 2522/4885KCNJ11 3021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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