SCHEMBL16709178

SCHEMBL16709178

C[C@H]1N(C)C=CN1CN1C=CN(c2ccccc2)[C@H]1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16711466 0.91 MAOA (0.34) MAPK1MAOA
SCHEMBL1834758 0.84 MAOA (0.36) MAPK1MAOA
SCHEMBL18250336 0.84 MAOA (0.36) MAPK1MAOA
SCHEMBL11941255 0.84 MAOA (0.36) MAPK1MAOA
SCHEMBL5285912 0.79 DRD2 (0.40) MAPK1MAOA
SCHEMBL16730238 0.79 CHRNA7 (0.36) MAPK1MAOA
SCHEMBL3458220 0.79 CHRNA7 (0.36) MAPK1MAOA
SCHEMBL15727400 0.78
SCHEMBL16709137 0.78
SCHEMBL5302977 0.77 RAB9A (0.38) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9306179-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-05 US disclosed
US-20150129840-A1 OSMIUM COMPLEXES COMPRISING THREE DIFFERENT BIDENTATE LIGANDS AND METHOD OF MAKING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2015-05-14 US disclosed