Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17207548 | 0.84 | TRPV1 (0.31) | TRPV1 | |
| SCHEMBL16709294 | 0.84 | LMNA (0.31) | TRPV1RAB9AL3MBTL1 | |
| SCHEMBL23862126 | 0.82 | POLB (0.33) | TRPV1RAB9AL3MBTL1 | |
| SCHEMBL12930114 | 0.80 | MAPT (0.41) | NPC1MAPTHTTRAB9AL3MBTL1 | |
| SCHEMBL16709292 | 0.80 | TRPV1 (0.33) | TRPV1 | |
| SCHEMBL12031053 | 0.78 | NPC1 (0.48) | NPC1RAB9ACYP1A2 | |
| SCHEMBL12930105 | 0.76 | IKBKB (0.36) | TRPV1NPC1RAB9ACYP1A2 | |
| SCHEMBL16709320 | 0.76 | CYP1A2 (0.34) | NPC1RAB9ACYP1A2 | |
| SCHEMBL20312891 | 0.76 | — | — | |
| SCHEMBL16711657 | 0.71 | MKNK1 (0.33) | NPC1MAPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179225-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-06-28 | — | — | US | disclosed |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-22 | — | — | US | disclosed |
| US-9458150-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150307517-A1 | ANTIMICROBIAL AGENTS | TAXIS PHARMACEUTICALS, INC. (US) | 2015-10-29 | — | — | US | disclosed |
| US-20150133465-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | TRPV1 1876/4885NPC1 516/4885MAPT 4729/4885 |
| US-20150133465-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | TRPV1 1876/4885NPC1 516/4885MAPT 4729/4885 |
| US-20150307517-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | TRPV1 1876/4885NPC1 516/4885MAPT 4729/4885 |
| US-20180179225-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | TRPV1 1876/4885NPC1 516/4885MAPT 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.