Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23862126 | 0.89 | POLB (0.33) | POLBRAB9AL3MBTL1TRPV1 | |
| SCHEMBL16711657 | 0.87 | MKNK1 (0.33) | LMNAPOLBRAB9AATML3MBTL1 | |
| SCHEMBL16709293 | 0.84 | TRPV1 (0.32) | RAB9AL3MBTL1TRPV1 | |
| SCHEMBL17207548 | 0.83 | TRPV1 (0.31) | TRPV1 | |
| SCHEMBL13080783 | 0.82 | NPC1 (0.44) | RAB9ATRPV1 | |
| SCHEMBL16709292 | 0.81 | TRPV1 (0.33) | TRPV1 | |
| SCHEMBL21104585 | 0.81 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL20312891 | 0.75 | — | — | |
| SCHEMBL16711659 | 0.74 | CACNA1H (0.35) | LMNAPOLBRAB9AL3MBTL1TRPV1 | |
| SCHEMBL20759392 | 0.73 | SMN1; SMN2 (0.38) | POLBRAB9ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129814-B2 | Antimicrobial agents | TAXIS PHARMACEUTICALS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20180179225-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-06-28 | — | — | US | disclosed |
| US-20180179225-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-06-28 | — | — | US | disclosed |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-22 | — | — | US | disclosed |
| US-9458150-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150307517-A1 | ANTIMICROBIAL AGENTS | TAXIS PHARMACEUTICALS, INC. (US) | 2015-10-29 | — | — | US | disclosed |
| US-20150133465-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129814-B2 | Antimicrobial agents | MRPL21, SPOUT1, LSS | LMNA 2883/4885POLB 186/4885RAB9A 1431/4885 |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | LMNA 2434/4885POLB 2530/4885RAB9A 2057/4885 |
| US-20150133465-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | LMNA 2434/4885POLB 2530/4885RAB9A 2057/4885 |
| US-20150307517-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | LMNA 2434/4885POLB 2530/4885RAB9A 2057/4885 |
| US-20180179225-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | LMNA 2434/4885POLB 2530/4885RAB9A 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.