Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12268166 | 0.80 | HCAR2 (0.43) | TOP2ATOP2BHCAR2THRBLMNA | |
| SCHEMBL16709802 | 0.79 | HCAR2 (0.37) | RAB9ATOP2ATOP2BHCAR2THRB | |
| SCHEMBL2556244 | 0.75 | HCAR2 (0.50) | HCAR2TDP1THRBLMNASMN1; SMN2 | |
| SCHEMBL21577435 | 0.75 | HCAR2 (0.50) | TOP2ATOP2BHCAR2TDP1THRB | |
| SCHEMBL16709780 | 0.75 | HCAR2 (0.50) | TOP2ATOP2BHCAR2TDP1THRB | |
| SCHEMBL16709763 | 0.74 | KDM4E (0.40) | RAB9ATOP2ATOP2BHCAR2THRB | |
| SCHEMBL28270005 | 0.73 | KDM4E (0.42) | RAB9AHCAR2THRBLMNANPC1 | |
| SCHEMBL16709796 | 0.72 | CYP2A6 (0.40) | TOP2ATOP2BHCAR2KMT2A | |
| SCHEMBL16709692 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL13052581 | 0.71 | CYP3A4 (0.44) | HCAR2THRBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015068839-A1 | POLYMERIZABLE COMPOUND, RESIN COMPOSITION USING SAME, CURED RESIN, AND OPTICAL MATERIAL | 新日鉄住金化学株式会社 | 2015-05-14 | — | — | WO | disclosed |