SCHEMBL16709692

SCHEMBL16709692

C=Cc1ccc(Sc2cncs2)cc1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.30
LRRK2 Q5S007 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415845 0.76 LRRK2 (0.42) ALDH1A1LRRK2
SCHEMBL1024003 0.72 ALDH1A1 (0.65) ALDH1A1TSHR
SCHEMBL9098570 0.72 HDAC8 (0.43)
SCHEMBL16709676 0.71 FBP1 (0.43) ALDH1A1TSHR
Lithium SCHEMBL30427541 0.70 ALDH1A1 (0.61) ALDH1A1TSHR
SCHEMBL942072 0.65 ALDH1A1 (0.59) ALDH1A1TSHR
SCHEMBL16709768 0.65 ALDH1A1 (0.59) ALDH1A1TSHR
SCHEMBL9335525 0.64
SCHEMBL14289218 0.63 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL16709773 0.63 ALDH1A1 (0.52) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015068839-A1 POLYMERIZABLE COMPOUND, RESIN COMPOSITION USING SAME, CURED RESIN, AND OPTICAL MATERIAL 新日鉄住金化学株式会社 2015-05-14 WO disclosed