Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671169 | 1.00 | ESR1 (0.34) | ESR1ESR2AR | |
| SCHEMBL1670168 | 0.82 | MGLL (0.36) | ESR1ESR2AR | |
| SCHEMBL1671170 | 0.82 | ESR1 (0.34) | ESR1ESR2AR | |
| SCHEMBL1682528 | 0.80 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL1682525 | 0.80 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL1670405 | 0.72 | KDM1A (0.30) | — | |
| SCHEMBL1670403 | 0.72 | KDM1A (0.30) | — | |
| SCHEMBL1671862 | 0.71 | ESR1 (0.36) | ESR1ESR2AR | |
| SCHEMBL1671861 | 0.71 | ESR1 (0.36) | ESR1ESR2AR | |
| SCHEMBL1670036 | 0.70 | PREP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |