Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | HTR1A | P08908 | 9/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16702266 | 0.92 | DRD2 (0.61) | DRD2SLC6A4HTR1AHRH3 | |
| SCHEMBL16712642 | 0.84 | HRH3 (0.55) | HRH3ACHERAD52 | |
| SCHEMBL3400205 | 0.81 | DRD2 (0.69) | DRD2SLC6A4HTR1A | |
| SCHEMBL10019232 | 0.80 | DRD2 (0.65) | DRD2SLC6A4HTR1A | |
| SCHEMBL3862596 | 0.80 | DRD2 (0.85) | DRD2HTR1A | |
| SCHEMBL254963 | 0.79 | DRD2 (0.70) | DRD2SLC6A4HTR1A | |
| SCHEMBL252470 | 0.78 | DRD2 (0.66) | DRD2SLC6A4HTR1AHRH3 | |
| SCHEMBL3407608 | 0.78 | DRD2 (0.74) | DRD2SLC6A4HTR1A | |
| SCHEMBL16701987 | 0.77 | DRD2 (0.59) | DRD2SLC6A4HTR1A | |
| SCHEMBL248100 | 0.77 | DRD2 (0.64) | DRD2SLC6A4HTR1AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015069110-A1 | MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS | AAPA B.V. (NL) | 2015-05-14 | — | — | WO | disclosed |