Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.59 |
| ▸ | HTR1A | P08908 | 16/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16701857 | 0.87 | DRD2 (0.55) | DRD2HTR1ASLC6A4HTR2AMCHR1 | |
| SCHEMBL16702159 | 0.85 | MAOA (0.41) | DRD2HTR1A | |
| SCHEMBL16703439 | 0.83 | HTR1A (0.53) | DRD2HTR1A | |
| SCHEMBL3862596 | 0.81 | DRD2 (0.85) | DRD2HTR1AHTR2AMCHR1 | |
| SCHEMBL16712645 | 0.80 | DRD2 (0.63) | DRD2HTR1ASLC6A4HTR2AMCHR1 | |
| SCHEMBL16712643 | 0.77 | DRD2 (0.62) | DRD2HTR1ASLC6A4 | |
| SCHEMBL16702266 | 0.77 | DRD2 (0.61) | DRD2HTR1ASLC6A4HTR2AMCHR1 | |
| SCHEMBL16703896 | 0.76 | DRD2 (0.46) | DRD2HTR1ASLC6A4HTR2AMCHR1 | |
| SCHEMBL12672777 | 0.75 | DRD2 (0.80) | DRD2HTR1ASLC6A4 | |
| SCHEMBL3859594 | 0.75 | DRD2 (0.74) | DRD2HTR1AHTR2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015069110-A1 | MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS | AAPA B.V. (NL) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015069110-A1 | MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS | AAPA B.V. (NL) | 2015-05-14 | — | — | WO | disclosed |